- A study of cisplatin nephrotoxicity.
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Young Hee Hwang, Kyoung A Lee, Son Moon Shin, Young Hoon Park, Jeong Ok Hah, Chun Dong Kim, Young Hwan Lee
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Yeungnam Univ J Med. 1992;9(2):327-333. Published online December 31, 1992
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DOI: https://doi.org/10.12701/yujm.1992.9.2.327
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- To evaluate the nephrotoxicity of cisplatin, serum levels of sodium, potassium, chloride, calcium, phosphorous, magnesium, BUN, creatinine and creatinine clearance were measured before and after administration of cisplatin in 18 cases of patients with malignant neoplasm. The results were as follows: 1) Serum calcium, magnesium, potassium and BUN levels were changed after cisplatin administration, but those changes were not statistically significant. 2) The mean value of creatinine clearance was not decreased significantly after treatment with cisplatin. 3) Acute renal failure was developed in one case, and four cases of hypocalcemia, hypomagnesemia were also detected after administration of cisplatin.
- The clinical observations in childhood asthma.
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Kih Yeon Song, Yong Hyoun Park, Jin Gon Jun, Young Hwan Lee, Chun Dong Kim
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Yeungnam Univ J Med. 1992;9(2):239-247. Published online December 31, 1992
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DOI: https://doi.org/10.12701/yujm.1992.9.2.239
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- A clinical analysis was done on 134 cases with bronchial asthma who were admitted to the Department of Pediatrics Yeungnam University from May 1987 to October 1991. The results were as follows: 1) The peak age of bronchial asthma was under 2 years. The sex ratio of male to female was 2.9:1. 2) The outbreak of bronchial asthma was most common in fall, especially in September. 3) The past history of other allergic diseases were present in 22.4% of patients (30/134 cases), and the previous bronchiolitis in infancy were experienced in 12.7% of patients (17/134 cases). 4) According to the skin test for allergens done by RAST, the most common allergens were Mites and House dust. 5) Eosinophilia (T.E.C>250/min) was found in 29.1%t of patients, and elevated lgE level (>200 IU/ml) was found in 63.2% of patients. 6) No significant differences in the serum lgE level were found between male and female patients. No significant differences in the serum lgE level were found between asthma patients with and without other allergic diseases. 7) The serum lgE level of school aged patients was significant higher than that of preschool aged (p<0.01).
- A Case of Neuroblastoma Presenting with Sudden Blindness.
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In Youl Ma, Jeong Ok Hah, Chun Dong Kim, Tae Sook Lee
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Yeungnam Univ J Med. 1985;2(1):259-264. Published online December 31, 1985
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DOI: https://doi.org/10.12701/yujm.1985.2.1.259
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- Neuroblastoma is the most common extracranial solid tumor of childhood which presents various clinical symptoms depending on the primary and metastatic sites. However, it has been rarely reported that sudden onset of blindness was the chief complaint of neuroblastoma. A four years old boy was admitted to the Yeungnam University Hospital with the chief complaint of a sudden onset of blindness due to a distant metastasis of abdominal neuroblastoma to the sphenoid sinus. On admission, both side pupils were dilated without light reflex, fundoscopy showed pale optic disk, electroretinogram was subnormal and visual evoked potential showed no response. The liver was palpable in 3 ½ finger breadth from the right costal margin and adult fist sized mass was palpable in the right flank. Skull X-ray showed destructed sphenoid bone and clinoid process and brain CT scan showed tumor mass in the sphenoid sinus and left orbit. Ultrasonogram and CT scan of the abdomen showed large tumor masses around the right kidney and para-aortic and retropancreatic lymph node. IVP showed displaced right calyceal system with preserved contour. Left supraclavicular lymph node which appeared after admission was biopsied and it showed poorly differentiated neuroblasts. He was treated according to the multiagent chemotherapy schedule for stage IV neuroblastoma patient of children's cancer study group. Abdominal tumor masses and sphenoid sinus mass were markedly reduced after 2 courses of the combination chemotherapy of cyclophosphamide, vincristine, DTIC, adriamycin and VM-26. Eventhough the blindness was not improved, the patient has been in good clinical codition.
- A Case of Alveolar Rhabdomyosarcoma Originating from the Chest Wall.
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Chun Dong Kim, Jeong Ok Hah, Hyun Mo Koo, Byung Ryul Choi, Han Ku Moon, Yong Hoon Park, Jin Gon Jun, Tae Sook Lee
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Yeungnam Univ J Med. 1984;1(1):207-212. Published online December 31, 1984
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DOI: https://doi.org/10.12701/yujm.1984.1.1.207
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- Rhabdomyosarcoma originating from the chest wall is a rare malignant tumor in children and was considered to be guarded in prognosis previously. However, recent advances in multidisciplinary treatment of rhabdomyosarcoma in children have improved the disease free survival rate. Authors report a case of alveolar rhabdomyosarcoma, stage III, originating from the chest wall who is surviving free of disease for 15 months with aggressive chemotherapy and radiotherapy.
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